D-Dimer Testing for the Exclusion of Pulmonary Embolism Among Hospitalized Patients With COVID-19

JAMA Netw Open. 2021 Oct 1;4(10):e2128802. doi: 10.1001/jamanetworkopen.2021.28802.

Authors

Constantine N Logothetis¹, Thomas A Weppelmann¹, Aryanna Jordan¹, Catherine Hanna², Sherry Zhang², Shaun Charkowick², Asa Oxner^{1

2}

Affiliations

¹ Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa.
² Morsani College of Medicine, University of South Florida, Tampa.

Abstract

This prognostic study evaluates the use of plasma D-dimer concentrations to rule out pulmonary embolism among patients hospitalized with COVID-19.

MeSH terms

Adult
Aged
Aged, 80 and over
Biomarkers / blood
COVID-19 / blood
COVID-19 / complications*
Clinical Decision Rules
Computed Tomography Angiography
Cross-Sectional Studies
Female
Fibrin Fibrinogen Degradation Products / metabolism*
Hospitalization
Humans
Male
Middle Aged
Pulmonary Embolism / blood
Pulmonary Embolism / diagnosis*
Pulmonary Embolism / virology
ROC Curve
Retrospective Studies

Substances

Biomarkers
Fibrin Fibrinogen Degradation Products
fibrin fragment D