Systems of pattern formation within developmental biology

Abstract

Applications of mathematical models to developmental biology have provided helpful insight into various subfields, ranging from the patterning of animal skin to the development of complex organ systems. Systems involved in patterning within morphology present a unique path to explain self-organizing systems. Current efforts show that patterning systems, notably Reaction-Diffusion and specific signaling pathways, provide insight for explaining morphology and could provide novel applications revolving around the formation of biological systems. Furthermore, the application of pattern formation provides a new perspective on understanding developmental biology and pathology research to study molecular mechanisms. The current review is to cover and take a more in-depth overlook at current applications of patterning systems while also building on the principles of patterning of future research in predictive medicine.

Keywords: Developmental biology; Morphology; Notch signaling; Reaction-diffusion.