Reduction of Infectivity of SARS-CoV-2 by Zinc Oxide Coatings

ACS Biomater Sci Eng. 2021 Nov 8;7(11):5022-5027. doi: 10.1021/acsbiomaterials.1c01076. Epub 2021 Oct 6.

Abstract

We developed antimicrobial coatings from ZnO particles that reduce the infectivity of SARS-CoV-2 suspensions by >99.9% in 1 h. The advantage of a coating is that it can be applied to a variety of objects, e.g., hand rails and door knobs, to hinder the spread of disease. Two porous coatings were prepared: one from submicrometer zinc oxide particles bound with silica menisci and the other from zinc oxide tetrapods bound with polyurethane. Experiments on glass coatings show that infectivity depends on porosity for hydrophilic materials, wherein aqueous droplets are imbibed into the pores.

Keywords: COVID-19; SARS-CoV-2; antiviral; coating; coronavirus; zinc oxide; zinc oxide tetrapod.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anti-Bacterial Agents
  • COVID-19*
  • Humans
  • SARS-CoV-2
  • Suspensions
  • Zinc Oxide* / pharmacology

Substances

  • Anti-Bacterial Agents
  • Suspensions
  • Zinc Oxide