Venom peptides - A comprehensive translational perspective in pain management

Curr Res Toxicol. 2021 Sep 9:2:329-340. doi: 10.1016/j.crtox.2021.09.001. eCollection 2021.

Abstract

Venom peptides have been evolving complex therapeutic interventions that potently and selectively modulate a range of targets such as ion channels, receptors, and signaling pathways of physiological processes making it potential therapeutic. Several venom peptides were deduced in vivo for clinical development targeting pain management, diabetes, cardiovascular diseases, antimicrobial activity. Several contributions have been detailed for a clear perspective for a better understanding of venomous animals, their venom, and their pharmacological effects. Here we unravel and summarize the recent advances in wide venom peptides across varieties of species for their therapeutics prospects.

Keywords: Inflammation; Nociception; Pain; Peptides; Snake venom; Toxicity; Toxins.

Publication types

  • Review