Hypertrophic pyloric stenosis case series in twins and first cousins: genes, feeding patterns or both? (a case report)

Pan Afr Med J. 2021 Jul 23:39:210. doi: 10.11604/pamj.2021.39.210.29180. eCollection 2021.

Abstract

We present two cases of dizygotic male twins and two cases of male first cousins with infantile hypertrophic pyloric stenosis (IHPS). All patients were treated with open pyloromyotomy. No complications were reported. The patients had the same risk factors for IHPS. First, all patients were first-born white males. Second, the twins were preterm (35 weeks). Third, the twins and the first cousins were exclusively bottle feeding. Thus, a combination of genetic and environmental factors may have contributed to the appearance of IHPS.

Keywords: Pyloric stenosis; case report; first cousins; twins.

Publication types

  • Case Reports

MeSH terms

  • Bottle Feeding*
  • Family
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Pyloric Stenosis, Hypertrophic / diagnosis*
  • Pyloric Stenosis, Hypertrophic / etiology
  • Pyloric Stenosis, Hypertrophic / surgery
  • Pyloromyotomy / methods*
  • Risk Factors
  • Twins, Dizygotic