Ligands with different properties and different selectivity are highly needed for in vitro and in vivo studies on the (patho)physiological influence of the chemical mediator histamine and its receptor subtypes. A selection of well-described ligands for the different receptor subtypes and different studies is shown with a particular focus on affinity and selectivity. In addition, compounds with radioactive or fluorescence elements will be presented with their beneficial use for other species or different investigations.
Keywords: Fluorescence; Histamine; Histamine H1 receptor; Histamine H2 receptor; Histamine H3 receptor; Histamine H4 receptor; PET; Radioligands.
© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.