Eliminating HIV transmission through breast milk from women taking antiretroviral drugs

Ameena E Goga; Philippe Van de Perre; Nobubelo Ngandu; Nicolas Nagot; Elaine J Abrams; Dhayendre Moodley; Rachel King; Jean-Pierre Molès; Witness Chirinda; Gabriella Scarlatti; Thorkild Tylleskär; Gayle G Sherman; Yogan Pillay; François Dabis; Glenda Gray

doi:10.1136/bmj.n1697

Eliminating HIV transmission through breast milk from women taking antiretroviral drugs

BMJ. 2021 Sep 29:374:n1697. doi: 10.1136/bmj.n1697.

Authors

Ameena E Goga^{1

2}, Philippe Van de Perre³, Nobubelo Ngandu⁴, Nicolas Nagot³, Elaine J Abrams⁵, Dhayendre Moodley^{6

7}, Rachel King^{3

8}, Jean-Pierre Molès³, Witness Chirinda⁴, Gabriella Scarlatti⁹, Thorkild Tylleskär¹⁰, Gayle G Sherman^{11

12}, Yogan Pillay¹³, François Dabis^{14

15}, Glenda Gray⁴

Affiliations

¹ South African Medical Research Council, Pretoria and Cape Town, South Africa Ameena.Goga@mrc.ac.za.
² University of Pretoria, Pretoria, South Africa.
³ Pathogenesis and Control of Chronic and Emerging Infections, University of Montpellier, INSERM, Etablissement Français du Sang; CHU Montpellier, Montpellier, France.
⁴ South African Medical Research Council, Pretoria and Cape Town, South Africa.
⁵ ICAP at Columbia, Mailman School of Public Health, Columbia University, New York, USA.
⁶ Department of Obstetrics and Gynaecology, School of Clinical Medicine, University of KwaZulu Natal, Durban, South Africa.
⁷ Centre for AIDS Research in South Africa, Durban, South Africa.
⁸ UCSF, San Francisco, CA, USA.
⁹ Viral Evolution and Transmission Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milan, Italy.
¹⁰ Centre for International Health, University of Bergen, Bergen, Norway.
¹¹ Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
¹² Centre for HIV & STI, National Institute for Communicable Diseases, National Health Laboratory Services, Johannesburg, South Africa.
¹³ Clinton Health Access Initiative, South Africa.
¹⁴ Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS), Paris, France.
¹⁵ Université Bordeaux, ISPED, Centre INSERM U1219-Bordeaux Population Health, Bordeaux, France.

Abstract

Ameena Goga and colleagues argue that frequent testing of maternal viral load is needed to eliminate HIV transmission through breast milk in low and middle income settings

MeSH terms

Anti-Retroviral Agents / therapeutic use*
Drug Monitoring
Female
HIV
HIV Infections / drug therapy
HIV Infections / transmission*
Humans
Infectious Disease Transmission, Vertical / prevention & control*
Milk, Human / virology*
Pregnancy
Pregnancy Complications, Infectious / drug therapy*
Viral Load

Substances

Anti-Retroviral Agents