Enantiopure helicene-porphyrin conjugates were prepared. They show strong changes in their circular dichroic response as compared to classical helicene derivatives, with highly intense bisignate Exciton Coupling (EC) signal and Δε values up to 680 M-1 cm-1 for the Soret band. They also display circularly polarized fluorescence in the (far-)red region, with dissymmetry factors up to 7 × 10-4.