Anti-hypertensive medication access and affordability and their association with blood pressure control at a teaching hospital in Ghana

Pan Afr Med J. 2021 Jul 8:39:184. doi: 10.11604/pamj.2021.39.184.27977. eCollection 2021.

Abstract

Introduction: many hypertensive patients require two or more anti-hypertensive drugs, but in low- and middle-income countries there may be challenges with medication access or affordability. The objective of this study was to determine accessibility and affordability of anti-hypertensive medicines and their association with blood pressure (BP) control among hypertensive patients attending the Korle-Bu teaching hospital (KBTH) polyclinic.

Methods: a cross-sectional study was conducted among 310 systematically sampled hypertensive patients attending the KBTH Polyclinic in Ghana. A structured questionnaire was used to obtain data on patient demographics and clinical characteristics, prices, availability and mode of payment of generic anti-hypertensive medicines.

Results: fifty-nine patients (19.4%) made out-of-pocket payments. At the private pharmacy and hospital, 123 (40.5%) and 77 patients (25.3%) respectively could not afford four anti-hypertensive medicines. Medicines availability at KBTH was 60%. Continuous access to BP drugs at KBTH was 14.8%. Overall access was 74.9% (SD ± 41.3). Out-of-pocket affordability of the medicines was positively correlated with BP control (R=0.12, p=0.037). Obtaining medicines via health insurance only was more likely to result in BP control than making any out-of-pocket payments (OR= 2.185; 95% CI, 1.215 - 3.927). Access at KBTH was more likely to result in BP control (OR=1.642; 95% C.I, 0.843 - 3.201).

Conclusion: there were access challenges although most patients obtained BP medication free. Out-of-pocket affordability is a challenge for some hypertensive patients. Access to affordable BP medication can improve BP control. These findings provide an impetus for urgently evaluating access to affordable anti-hypertensive medicines in other hospitals in Ghana.

Keywords: Affordability; anti-hypertensive; blood pressure; health insurance; hypertension.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antihypertensive Agents / administration & dosage*
  • Antihypertensive Agents / economics
  • Antihypertensive Agents / supply & distribution
  • Blood Pressure / drug effects
  • Costs and Cost Analysis
  • Cross-Sectional Studies
  • Drugs, Generic / administration & dosage*
  • Drugs, Generic / economics
  • Drugs, Generic / supply & distribution
  • Female
  • Ghana
  • Health Expenditures / statistics & numerical data
  • Health Services Accessibility / economics*
  • Hospitals, Teaching
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / economics
  • Insurance, Health / statistics & numerical data
  • Male
  • Middle Aged
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Antihypertensive Agents
  • Drugs, Generic