The Influence of Propolis on Dental Plaque Reduction and the Correlation between Dental Plaque and Severity of COVID-19 Complications-A Literature Review

Molecules. 2021 Sep 11;26(18):5516. doi: 10.3390/molecules26185516.

Abstract

Current studies suggest that cariogenic bacteria in dental plaque influence the severity of COVID-19 complications since the oral cavity is a reservoir for respiratory pathogens potentially responsible for the development of hospital-acquired pneumonia. This article focuses on the association between dental plaque and COVID-19 concerning the influence of altered oral biofilm on the risk of increased severity of SARS-CoV-2 infection. Moreover, it concentrates on the usefulness of propolis, with its apitherapeutic antibacterial properties, for treating oral bacterial infections co-occurring with SARS-CoV-2 infection. A review of the literature on PubMed, Cochrane Library and Medline between 2000 and 2021 revealed 56 published articles indicating that a link between dental plaque and COVID-19 complications was probable. Furthermore, they indicated that propolis may minimize COVID-19 severity by reducing dental plaque accumulation. The possibility that improved oral health could reduce the risk of COVID-19 complications should be of interest to scientists.

Keywords: COVID-19 complications; dental caries; dental plaque; propolis.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents / therapeutic use
  • Biofilms* / drug effects
  • COVID-19 Drug Treatment*
  • COVID-19* / microbiology
  • Dental Caries* / drug therapy
  • Dental Caries* / microbiology
  • Dental Plaque* / drug therapy
  • Dental Plaque* / microbiology
  • Humans
  • Mouth Diseases* / drug therapy
  • Mouth Diseases* / microbiology
  • Oral Health
  • Propolis / therapeutic use*

Substances

  • Anti-Infective Agents
  • Propolis