Arrhythmic manifestation in β-thalassemia cardiomyopathy: a complex management

J Cardiovasc Med (Hagerstown). 2021 Dec 1;22(12):e41-e42. doi: 10.2459/JCM.0000000000001265.

Abstract

A young male with β-thalassemia major was implanted with a single-chamber Implantable cardioverter-defibrillator (ICD) for a cardiac arrest due to ventricular fibrillation. He received multiple inappropriate shocks due to atrioventricular nodal re-entrant tachycardia (AVNRT) treated with radiofrequency catheter ablation and then to high-rate atrial tachycardia refractory to amiodarone and not inducible during electrophysiological study. He refused empirical pulmonary vein isolation. Upgrading to biventricular ICD and performing atrioventricular node ablation avoided further inappropriate shocks.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Atrioventricular Node / physiopathology
  • Atrioventricular Node / surgery
  • Blood Transfusion / methods
  • Catheter Ablation / methods*
  • Defibrillators, Implantable / adverse effects*
  • Humans
  • Hypertrophy, Left Ventricular* / diagnostic imaging
  • Hypertrophy, Left Ventricular* / etiology
  • Hypertrophy, Left Ventricular* / physiopathology
  • Iron Overload* / diagnosis
  • Iron Overload* / etiology
  • Magnetic Resonance Imaging, Cine / methods
  • Male
  • Tachycardia, Supraventricular* / etiology
  • Tachycardia, Supraventricular* / physiopathology
  • Tachycardia, Supraventricular* / therapy
  • Treatment Outcome
  • beta-Thalassemia* / complications
  • beta-Thalassemia* / therapy