Correlation of anthropometric index and cardiopulmonary exercise testing in children with pectus excavatum

F Oleksak; B Spakova; A Durdikova; P Durdik; T Kralova; M Igaz; M Molnar; M Gura; D Murgas

doi:10.1016/j.resp.2021.103790

Correlation of anthropometric index and cardiopulmonary exercise testing in children with pectus excavatum

Respir Physiol Neurobiol. 2022 Feb:296:103790. doi: 10.1016/j.resp.2021.103790. Epub 2021 Sep 21.

Authors

F Oleksak¹, B Spakova², A Durdikova³, P Durdik³, T Kralova³, M Igaz³, M Molnar², M Gura², D Murgas²

Affiliations

¹ Clinic for Children and Adolescents, University Hospital in Martin, Jessenius Medical Faculty in Martin, Commenius University in Bratislava, Kollarova 2, 036 59, Martin, Slovakia. Electronic address: oleksak3@uniba.sk.
² Clinic of Pediatric Surgery, University Hospital in Martin, Jessenius Medical Faculty in Martin, Commenius University in Bratislava, Kollarova 2, 036 59, Martin, Slovakia.
³ Clinic for Children and Adolescents, University Hospital in Martin, Jessenius Medical Faculty in Martin, Commenius University in Bratislava, Kollarova 2, 036 59, Martin, Slovakia.

PMID: 34560293
DOI: 10.1016/j.resp.2021.103790

Abstract

Background: Cardiopulmonary exercise testing (CPET) is a method used to evaluate functional impairment of patients with various diseases.

Objective: The objective was to use CPET to estimate the usability of anthropometric index (AI) in patients with pectus excavatum (PE) as a marker of functional impairment caused by chest deformity.

Methods: The study included 32 paediatric patients (28 males) with PE. Patients underwent CPET using a breath-by-breath exhaled gas analysis method and continuous monitoring of cardiac parameters.

Results: In both groups, two (overall four) patients met criteria for cardiogenic limitation (low VO₂ and low O₂Pulse). Mean VO₂/WR was below two standard deviations (2SD) in patients with less severe PE; other observed parameters were within normal limits (Z-score ± 2 SD). The AI had no observed correlation with peak ventilation, VO₂peak and peak workload.

Conclusion: The obtained CPET data do not correlate well with the severity of chest deformity expressed with AI. There were similar physical activity limitations in both examined groups of patients and they did not depend on the severity of the deformity.

Keywords: Anthropometric index; Cardiopulmonary exercise testing; Pectus excavatum.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anthropometry
Child
Exercise Test
Female
Funnel Chest / diagnosis*
Funnel Chest / physiopathology*
Humans
Male
Severity of Illness Index*