The use of super-selective uterine artery branch embolization and methotrexate in cervical pregnancy - case reports and literature review

Ann Agric Environ Med. 2021 Sep 16;28(3):521-524. doi: 10.26444/aaem/127926. Epub 2020 Oct 7.

Abstract

Cervical ectopic pregnancy (CEP) is one of the rarest types of ectopic pregnancy. Early detection of such cases increases the chances of conservative treatment and fertility preservation. Within 6 weeks of each other, 2 women were admitted to the OB/GYN Department with cervical ectopic pregnancies. They were successfully treated with a double dose of methotrexate and super-selective uterine artery branch embolization (SUABE). Taking into account health and economic considerations, for instance the optimal recovery time, and lower costs of operating theater time, laboratory testing and outpatient observation, it seems that safe, minimally invasive, fertility-saving, effective systemic administration of MTX in combination with SUABE, can be a rational alternative to cervical ectopic pregnancy treatment.

Keywords: Methotrexate; cervical ectopic pregnancy; super-selective uterine artery branch embolization; uterine artery embolization.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Cervix Uteri / blood supply
  • Cervix Uteri / surgery*
  • Female
  • Humans
  • Methotrexate / administration & dosage*
  • Pregnancy
  • Pregnancy, Ectopic / drug therapy
  • Pregnancy, Ectopic / surgery*
  • Uterine Artery / drug effects
  • Uterine Artery / surgery*
  • Uterine Artery Embolization

Substances

  • Methotrexate