Successful Endoscopic Sclerotherapy Using Lauromacrogol Injection for Laryngopharyngeal Hemangioma

Ear Nose Throat J. 2021 Nov;100(9):662-666. doi: 10.1177/01455613211043690. Epub 2021 Sep 22.

Abstract

Objectives: This study aims to investigate the efficacy and safety of local lauromacrogol injection in the treatment of hypopharyngeal hemangioma. Methods: From Aug 2015 to May 2021, 13 consecutive patients suffering from hypopharyngeal hemangioma underwent local lauromacrogol injection assisted by endoscope in this prospective clinical series. All patients were followed up regularly and the therapeutic effects and complications were observed. Results: A total 13 of patients were enrolled, including 11 men and 2 women, with an average age of 48.5 years (range 25-76 years). The sizes of the hemangioma ranged from 0.5 × 1.0 cm to 3.5 × 3.5 cm. After 1 to 40 months of follow-up, 12 patients were cured and 1 was significantly effective after 1 to 4 (mean 1.8) injections. All patients suffered varying degrees of postoperative pain or foreign body sensation. 3 patients were significantly affected by local swelling of the injection site, 2 of which underwent prophylactic tracheostomy postoperatively and 1 patient returned to the ward with endotracheal intubation postoperatively. No complications such as mucosal ulceration, fever, and allergies occurred. Conclusions: Lauromacrogol injection is a safe and effective method to treat hypopharyngeal hemangioma.

Keywords: endoscopy; hemangioma; hypopharyngeal; lauromacrogol.

MeSH terms

  • Adult
  • Aged
  • Endoscopy
  • Female
  • Hemangioma / therapy*
  • Humans
  • Hypopharyngeal Neoplasms / therapy*
  • Injections
  • Male
  • Middle Aged
  • Polidocanol / administration & dosage*
  • Sclerosing Solutions / administration & dosage*
  • Sclerotherapy / methods*

Substances

  • Sclerosing Solutions
  • Polidocanol