Ocular involvement and complications of lichen planus, lichen planus pigmentosus, and lichen planopilaris: A comprehensive review

Dermatol Ther. 2021 Nov;34(6):e15137. doi: 10.1111/dth.15137. Epub 2021 Sep 25.

Abstract

Ocular involvement of lichenoid dermatoses, such as lichen planus (LP), lichen planus pigmentosus (LPP), and lichen planopilaris (LPL), although uncommon, is associated with skin manifestations. Isolated ocular involvement is very rare. When lesions are confined to the skin, the dermatologist inquires and evaluates for oral and genital symptoms and lesions, respectively; hence, eye manifestations are commonly neglected by the non-ophthalmologist. Ocular involvement in LP, LPP, and LPL may result in significant morbidity. An ophthalmic interrogatory and a gross ophthalmic evaluation performed by the dermatologist may unravel ocular signs and symptoms that require evaluation by an eye specialist. Ocular surface inflammation and scarring, when untreated, results in serious complications such as corneal perforation and permanent vision loss. This review aims to present an up-to-date overview for the dermatologist of the ocular involvement and complications of LP, LPP, and LPL, and when to refer to the ophthalmologist to prevent blinding complications.

Keywords: conjunctival scarring; dry eye disease; lichen planopilaris; lichen planus; lichen planus pigmentosus; ocular involvement; ocular surface.

Publication types

  • Review

MeSH terms

  • Face
  • Humans
  • Hyperpigmentation*
  • Lichen Planus* / complications
  • Lichen Planus* / diagnosis
  • Lichen Planus* / pathology
  • Skin / pathology