A Rare Case of Primary Small Cell Carcinoma of Esophagus

Cureus. 2021 Aug 15;13(8):e17190. doi: 10.7759/cureus.17190. eCollection 2021 Aug.

Abstract

Primary small cell carcinoma of the esophagus is a rare, highly aggressive disease with a poor prognosis. A definitive diagnosis is made by histopathological study. As the disease is usually metastatic, palliative chemoradiotherapy is the usual treatment. We present a case of a 57-year-old female presenting with dysphagia. The patient underwent imaging studies showing the growth at the gastro-esophageal junction, with extensive abdominal lymph node metastasis and liver and lung metastasis. Biopsy was suggestive of small cell carcinoma of the esophagus. The patient underwent a feeding jejunostomy and was planned for chemoradiotherapy. Primary small cell carcinoma of the esophagus is an infrequent entity. As the disease is usually diagnosed at a later stage, the prognosis is inferior and abysmal.

Keywords: carcinoma esophagus; chromogranin; dysphagia; neuroendocrine tumor; small cell carcinoma; synaptophysin.

Publication types

  • Case Reports