Preterm and term prelabour rupture of membranes: A review of timing and methods of labour induction

Pierre Delorme; Elsa Lorthe; Jeanne Sibiude; Gilles Kayem

doi:10.1016/j.bpobgyn.2021.08.009

Preterm and term prelabour rupture of membranes: A review of timing and methods of labour induction

Best Pract Res Clin Obstet Gynaecol. 2021 Nov:77:27-41. doi: 10.1016/j.bpobgyn.2021.08.009. Epub 2021 Sep 3.

Authors

Pierre Delorme¹, Elsa Lorthe², Jeanne Sibiude³, Gilles Kayem⁴

Affiliations

¹ Sorbonne Université, AP-HP, Department of Gynaecology and Obstetrics, Trousseau Hospital, Paris, France; INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité (CRESS), FHU PREMA, Paris Descartes University, Paris, France.
² INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité (CRESS), FHU PREMA, Paris Descartes University, Paris, France; Unit of Population Epidemiology, Department of Primary Care Medicine, Geneva University Hospitals, 1205, Geneva, Switzerland.
³ Université de Paris, IAME, INSERM, F-75018, Paris, France; AP-HP, Hôpital Louis Mourier, Service de Gynécologie-Obstétrique, F-92700, Colombes, France.
⁴ Sorbonne Université, AP-HP, Department of Gynaecology and Obstetrics, Trousseau Hospital, Paris, France; INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité (CRESS), FHU PREMA, Paris Descartes University, Paris, France. Electronic address: gkayem@gmail.com.

PMID: 34538740
DOI: 10.1016/j.bpobgyn.2021.08.009

Abstract

Prelabour rupture of membranes (PROM) exposes both foetuses and mothers to the risk of infection. Induction of labour has been proposed to reduce this risk, but its neonatal and maternal risks and benefits must be balanced against those of expectant management (EM). Recent randomized studies of preterm PROM show that EM until 37 weeks of gestation is associated with lower overall neonatal morbidity. In term PROM, active management is associated with a shorter birth interval but not with lower rates of neonatal infection. Similar maternal and neonatal outcomes are reported regardless of whether induction uses oxytocin, PGE2, or oral misoprostol.

Keywords: Caesarean birth; Induced; Prelabour rupture of membranes; Premature rupture; Preterm; Term.

Publication types

Review

MeSH terms

Female
Fetal Membranes, Premature Rupture* / therapy
Humans
Infant, Newborn
Labor, Induced
Misoprostol*
Oxytocin
Pregnancy

Substances

Misoprostol
Oxytocin