Latching dynamics as a basis for short-term recall

PLoS Comput Biol. 2021 Sep 15;17(9):e1008809. doi: 10.1371/journal.pcbi.1008809. eCollection 2021 Sep.

Abstract

We discuss simple models for the transient storage in short-term memory of cortical patterns of activity, all based on the notion that their recall exploits the natural tendency of the cortex to hop from state to state-latching dynamics. We show that in one such model, and in simple spatial memory tasks we have given to human subjects, short-term memory can be limited to similar low capacity by interference effects, in tasks terminated by errors, and can exhibit similar sublinear scaling, when errors are overlooked. The same mechanism can drive serial recall if combined with weak order-encoding plasticity. Finally, even when storing randomly correlated patterns of activity the network demonstrates correlation-driven latching waves, which are reflected at the outer extremes of pattern space.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / methods
  • Humans
  • Memory, Short-Term*
  • Mental Recall*
  • Models, Neurological

Grants and funding

Work supported by Human Frontier Science Program Grant RGP0057/2016 (AT) and by EU Marie Skłodowska-Curie Training Network 765549 M-Gate (AT, OS). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.