Spontaneous recovery of immune checkpoint inhibitor-induced thyroiditis with high free T4 level: A case report

Rie Hagiwara; Daisuke Suzuki; Shiori Tonezawa; Rika Saikawa; Shunsuke Funazaki; Masashi Yoshida; Satoshi Washino; Tomoaki Miyagawa; Kazuo Hara; Hodaka Yamada

doi:10.1002/ccr3.4781

Spontaneous recovery of immune checkpoint inhibitor-induced thyroiditis with high free T4 level: A case report

Clin Case Rep. 2021 Sep 7;9(9):e04781. doi: 10.1002/ccr3.4781. eCollection 2021 Sep.

Affiliations

¹ Department of Endocrinology and Metabolism Jichi Medical University Saitama Medical Center Saitama Japan.
² Department of Urology Jichi Medical University Saitama Medical Center Saitama Japan.

Abstract

We describe a case of severe hyperthyroidism with high free thyroxine and C-reactive protein levels, wherein thyroid function rapidly improved without treatment. In a similar case, conservative management with imaging follow-up can be considered.

Keywords: high CRP level; high free T4 level; immune checkpoint inhibitors (ICI); thyroiditis; without steroids.

Publication types

Case Reports