Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up

S J Strauss; A M Frezza; N Abecassis; J Bajpai; S Bauer; R Biagini; S Bielack; J Y Blay; S Bolle; S Bonvalot; I Boukovinas; J V M G Bovee; K Boye; B Brennan; T Brodowicz; A Buonadonna; E de Álava; A P Dei Tos; X Garcia Del Muro; A Dufresne; M Eriksson; F Fagioli; A Fedenko; V Ferraresi; A Ferrari; N Gaspar; S Gasperoni; H Gelderblom; F Gouin; G Grignani; A Gronchi; R Haas; A B Hassan; S Hecker-Nolting; N Hindi; P Hohenberger; H Joensuu; R L Jones; C Jungels; P Jutte; L Kager; B Kasper; A Kawai; K Kopeckova; D A Krákorová; A Le Cesne; F Le Grange; E Legius; A Leithner; A López Pousa; J Martin-Broto; O Merimsky; C Messiou; A B Miah; O Mir; M Montemurro; B Morland; C Morosi; E Palmerini; M A Pantaleo; R Piana; S Piperno-Neumann; P Reichardt; P Rutkowski; A A Safwat; C Sangalli; M Sbaraglia; S Scheipl; P Schöffski; S Sleijfer; D Strauss; K Sundby Hall; A Trama; M Unk; M A J van de Sande; W T A van der Graaf; W J van Houdt; T Frebourg; R Ladenstein; P G Casali; S Stacchiotti; ESMO Guidelines Committee, EURACAN, GENTURIS and ERN PaedCan. Electronic address: clinicalguidelines@esmo.org

doi:10.1016/j.annonc.2021.08.1995

Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up

Ann Oncol. 2021 Dec;32(12):1520-1536. doi: 10.1016/j.annonc.2021.08.1995. Epub 2021 Sep 6.

Authors

S J Strauss¹, A M Frezza², N Abecassis³, J Bajpai⁴, S Bauer⁵, R Biagini⁶, S Bielack⁷, J Y Blay⁸, S Bolle⁹, S Bonvalot¹⁰, I Boukovinas¹¹, J V M G Bovee¹², K Boye¹³, B Brennan¹⁴, T Brodowicz¹⁵, A Buonadonna¹⁶, E de Álava¹⁷, A P Dei Tos¹⁸, X Garcia Del Muro¹⁹, A Dufresne²⁰, M Eriksson²¹, F Fagioli²², A Fedenko²³, V Ferraresi²⁴, A Ferrari²⁵, N Gaspar²⁶, S Gasperoni²⁷, H Gelderblom²⁸, F Gouin²⁹, G Grignani³⁰, A Gronchi³¹, R Haas³², A B Hassan³³, S Hecker-Nolting⁷, N Hindi³⁴, P Hohenberger³⁵, H Joensuu³⁶, R L Jones³⁷, C Jungels³⁸, P Jutte³⁹, L Kager⁴⁰, B Kasper³⁵, A Kawai⁴¹, K Kopeckova⁴², D A Krákorová⁴³, A Le Cesne⁴⁴, F Le Grange¹, E Legius⁴⁵, A Leithner⁴⁶, A López Pousa⁴⁷, J Martin-Broto³⁴, O Merimsky⁴⁸, C Messiou⁴⁹, A B Miah⁵⁰, O Mir⁵¹, M Montemurro⁵², B Morland⁵³, C Morosi⁵⁴, E Palmerini⁵⁵, M A Pantaleo⁵⁶, R Piana⁵⁷, S Piperno-Neumann⁵⁸, P Reichardt⁵⁹, P Rutkowski⁶⁰, A A Safwat⁶¹, C Sangalli⁶², M Sbaraglia¹⁸, S Scheipl⁴⁶, P Schöffski⁶³, S Sleijfer⁶⁴, D Strauss⁶⁵, K Sundby Hall¹³, A Trama⁶⁶, M Unk⁶⁷, M A J van de Sande⁶⁸, W T A van der Graaf⁶⁹, W J van Houdt⁷⁰, T Frebourg⁷¹, R Ladenstein³⁹, P G Casali⁷², S Stacchiotti²; ESMO Guidelines Committee, EURACAN, GENTURIS and ERN PaedCan. Electronic address: clinicalguidelines@esmo.org

Affiliations

¹ Department of Oncology, University College London Hospitals NHS Foundation Trust (UCLH), London, UK.
² Department of Cancer Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
³ Instituto Portugues de Oncologia de Lisboa Francisco Gentil, EPE, Lisbon, Portugal.
⁴ Department of Medical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.
⁵ Department of Medical Oncology, Interdisciplinary Sarcoma Center, West German Cancer Center, University of Duisburg-Essen, Essen, Germany.
⁶ Department of Oncological Orthopedics, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
⁷ Klinikum Stuttgart-Olgahospital, Stuttgart, Germany.
⁸ Centre Leon Berard and UCBL1, Lyon, France.
⁹ Radiation Oncology Department, Gustave Roussy, Villejuif, France.
¹⁰ Department of Surgery, Institut Curie, Paris, France.
¹¹ Bioclinic Thessaloniki, Thessaloniki, Greece.
¹² Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
¹³ Department of Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway.
¹⁴ Paediatric Oncology, Royal Manchester Children's Hospital, Manchester, UK.
¹⁵ Vienna General Hospital (AKH), Medizinische Universität Wien, Vienna, Austria.
¹⁶ Centro di Riferimento Oncologico di Aviano, Aviano, Italy.
¹⁷ Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocio University Hospital, CSIC, University of Sevilla, CIBERONC, Seville, Spain; Department of Normal and Pathological Cytology and Histology, School of Medicine, University of Seville, Seville, Spain.
¹⁸ Department of Pathology, Azienda Ospedale Università Padova, Padua, Italy.
¹⁹ Integrated Unit ICO Hospitalet, HUB, Barcelona, Spain.
²⁰ Département d'Oncologie Médicale Centre Leon Berard, Lyon, France.
²¹ Skane University Hospital-Lund, Lund, Sweden.
²² Paediatric Onco-Haematology Department, Regina Margherita Children's Hospital, Department of Public Health and Pediatrics, University of Turin, Turin, Italy.
²³ P.A. Herzen Cancer Research Institute, Moscow, Russian Federation.
²⁴ Sarcomas and Rare Tumors Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
²⁵ Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
²⁶ Department of Oncology for Child and Adolescents, Gustave Roussy Cancer Center, Paris-Saclay University, Villejuif, France.
²⁷ Department of Oncology and Robotic Surgery, Azienda Ospedaliera Universitaria Careggi, Florence, Italy.
²⁸ Department of Medical Oncology, Leiden University Medical Centre, Leiden, The Netherlands.
²⁹ Centre Leon-Berard Lyon, Lyon, France.
³⁰ Candiolo Cancer Institute, FPO - IRCCS, Candiolo, Italy.
³¹ Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori and University of Milan, Milan, Italy.
³² Department of Radiotherapy, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Radiotherapy, Leiden University Medical Centre, Leiden, The Netherlands.
³³ Oxford University Hospitals NHS Foundation Trust and University of Oxford, Oxford, UK.
³⁴ Department of Medical Oncology, Fundación Jimenez Diaz, University Hospital, Advanced Therapies in Sarcoma Lab, Madrid, Spain.
³⁵ Mannheim University Medical Center, Mannheim, Germany.
³⁶ Helsinki University Hospital (HUH) and University of Helsinki, Helsinki, Finland.
³⁷ Sarcoma Unit, Royal Marsden Hospital and Institute of Cancer Research, London, UK.
³⁸ Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
³⁹ University Medical Center Groningen, Groningen, The Netherlands.
⁴⁰ St. Anna Children's Hospital and Children's Cancer Research Institute (CCRI), Department of Pediatrics and Medical University Vienna Children's Cancer Research Institute, Vienna, Austria.
⁴¹ Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan.
⁴² University Hospital Motol, Prague, Czech Republic.
⁴³ Masaryk Memorial Cancer Institute, Brno, Czech Republic.
⁴⁴ Department of Cancer Medicine, Gustave Roussy, Villejuif, France.
⁴⁵ Department for Human Genetics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
⁴⁶ Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria.
⁴⁷ Medical Oncology Department, Hospital Universitario Santa Creu i Sant Pau, Barcelona, Spain.
⁴⁸ Tel Aviv Sourasky Medical Center (Ichilov), Tel Aviv, Israel.
⁴⁹ Department of Radiology, Royal Marsden Hospital and Institute of Cancer Research, London, UK.
⁵⁰ Department of Oncology, Royal Marsden Hospital and Institute of Cancer Research, London, UK.
⁵¹ Department of Ambulatory Cancer Care, Gustave Roussy, Villejuif, France.
⁵² Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
⁵³ Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
⁵⁴ Department of Radiology, IRCCS Foundation National Cancer Institute, Milan, Italy.
⁵⁵ Department of Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
⁵⁶ Division of Oncology, IRCCS Azienda Ospedaliero-Universitaria, di Bologna, Bologna, Italy.
⁵⁷ Azienda Ospedaliero, Universitaria Cita della Salute e della Scienza di Torino, Turin, Italy.
⁵⁸ Department of Medical Oncology, Institut Curie, Paris, France.
⁵⁹ Helios Klinikum Berlin Buch, Berlin, Germany.
⁶⁰ Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
⁶¹ Aarhus University Hospital, Aarhus, Denmark.
⁶² Department of Radiotherapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
⁶³ Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium.
⁶⁴ Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
⁶⁵ Department of Surgery, Royal Marsden Hospital, London, UK.
⁶⁶ Department of Research, Evaluative Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
⁶⁷ Institute of Oncology of Ljubljana, Ljubljana, Slovenia.
⁶⁸ Department of Orthopedic Surgery, Leiden University Medical Center, Leiden, The Netherlands.
⁶⁹ Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
⁷⁰ Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
⁷¹ Department of Genetics, Normandy Center for Genomic and Personalized Medicine, Normandie Univ, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France.
⁷² Department of Cancer Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy; Department of Oncology and Hemato-oncology University of Milan, Milan, Italy.

PMID: 34500044
DOI: 10.1016/j.annonc.2021.08.1995

No abstract available

Keywords: bone sarcoma; clinical practice guideline; diagnosis; follow-up; management; treatment.

Publication types

Practice Guideline
Research Support, Non-U.S. Gov't

MeSH terms

Bone Neoplasms* / diagnosis
Bone Neoplasms* / epidemiology
Bone Neoplasms* / therapy
Follow-Up Studies
Humans
Osteosarcoma* / diagnosis
Osteosarcoma* / epidemiology
Osteosarcoma* / therapy
Sarcoma* / diagnosis
Sarcoma* / epidemiology
Sarcoma* / therapy