Causal Associations Between Blood Lipids and COVID-19 Risk: A Two-Sample Mendelian Randomization Study

Arterioscler Thromb Vasc Biol. 2021 Nov;41(11):2802-2810. doi: 10.1161/ATVBAHA.121.316324. Epub 2021 Sep 9.

Authors

Kun Zhang^#^{1

2}, Shan-Shan Dong^#², Yan Guo^{1

2}, Shi-Hao Tang², Hao Wu², Shi Yao², Peng-Fei Wang¹, Kun Zhang¹, Han-Zhong Xue¹, Wei Huang¹, Jian Ding², Tie-Lin Yang^{1

2}

Affiliations

¹ Department of Trauma Surgery, Honghui Hospital, College of Medicine (K.Z., Y.G., P.-F.W., K.Z., H.-Z.X., W.H., T.-L.Y.), Xi'an Jiaotong University, Shaanxi, PR China.
² Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology (K.Z., S.-S.D., Y.G., S.-H.T., H.W., S.Y., J.D., T.-L.Y.), Xi'an Jiaotong University, Shaanxi, PR China.

^# Contributed equally.

Abstract

[Figure: see text].

Keywords: blood; cholesterol; coronavirus; dyslipidemias; lipids.

MeSH terms

Apolipoproteins B / blood
COVID-19 / blood*
COVID-19 / complications*
Cholesterol / blood
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Disease Susceptibility
Dyslipidemias / complications*
Humans
Lipids / blood*
Mendelian Randomization Analysis
Risk Factors
SARS-CoV-2
Severity of Illness Index

Substances

Apolipoproteins B
Cholesterol, HDL
Cholesterol, LDL
Lipids
Cholesterol

Grants and funding