Health Risk Assessment of Heavy Metals (Pb, Cd, Hg) in Hydroalcoholic Gels of Abidjan, Côte d'Ivoire

Biol Trace Elem Res. 2022 May;200(5):2510-2518. doi: 10.1007/s12011-021-02822-y. Epub 2021 Sep 7.

Abstract

Despite the high consumption of hydroalcoholic gels worldwide and particularly in Côte d'Ivoire since the outbreak of the COVID-19 pandemic, very few studies have measured the heavy metal content and human exposure in this product. Thus, 30 samples from supermarkets in Abidjan, Côte d'Ivoire, were collected for the study of risk assessment of exposure to heavy metals contained in hydroalcoholic gels. This study consists of the characterization of the danger by calculating the carcinogenic and non-carcinogenic risk by skin contact. Almost all samples analysed contain trace of lead, cadmium and mercury but at concentrations below the Canadian limit in cosmetic products applied to the skin and below the US FDA limit as an impurity in colour additives used in cosmetic products. The mean values of chronic daily intake via dermal absorption (CDIdermal) for adults were found in the order of mercury > lead > cadmium. The health risk estimation indicated that the mean total hazard quotient for dermal adsorption (HIdermal) obtained is 7.10 × 10-5 ± 5.52 × 10-5. This value was below 1, the acceptable limit, representing a non-carcinogenic risk for Abidjan residents through dermal adsorption. Moreover, the incremental lifetime cancer risk (ILCR) evaluation for lead and cadmium was insignificant, and the cancer risk can be neglected, but in case of their overusing, they can cause long-term health problems for consumers.

Keywords: Carcinogenic; Dermal adsorption; Health risk; Heavy metals; Hydroalcoholic gel; Non-carcinogenic health risk.

MeSH terms

  • Adult
  • COVID-19*
  • Cadmium / analysis
  • Canada
  • Cote d'Ivoire / epidemiology
  • Environmental Monitoring
  • Gels / analysis
  • Humans
  • Lead / analysis
  • Mercury* / analysis
  • Metals, Heavy* / analysis
  • Neoplasms*
  • Pandemics
  • Risk Assessment

Substances

  • Gels
  • Metals, Heavy
  • Cadmium
  • Lead
  • Mercury