Metabolomics can provide new insights into perinatal nutrition

Acta Paediatr. 2023 Feb;112(2):233-241. doi: 10.1111/apa.16096. Epub 2021 Sep 13.

Abstract

Perinatal nutrition is a key factor related to the Developmental Origin of Health and Disease hypothesis, which states that each and every event that happens during the periconceptional period and pregnancy can affect the health status of an individual. Metabolomics can be a very useful tool for gathering information about the effect of perinatal nutrition on both mothers and newborn infants. This non-systematic review focuses on the main metabolites detected by this technique, with regard to gestational diabetes, intrauterine growth restriction and breast milk. Conclusion. Nutrition, metabolome and microbiome interactions are gaining interest in the scientific community.

Keywords: breast milk; gestational diabetes; intrauterine growth restriction; metabolomics; perinatal nutrition.

Publication types

  • Review

MeSH terms

  • Diabetes, Gestational*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Metabolome
  • Metabolomics*
  • Milk, Human / metabolism
  • Mothers
  • Pregnancy