Laser Therapy in the Treatment of Diabetic Retinopathy and Diabetic Macular Edema

Curr Diab Rep. 2021 Sep 6;21(9):35. doi: 10.1007/s11892-021-01403-6.

Abstract

Purpose of review: This review highlights indications and evidence on laser therapy in the management of diabetic retinopathy and diabetic macular edema. Particular focus is placed upon the benefits and limitations of conventional laser photocoagulation versus more modern laser photocoagulation techniques, as well as the role of laser photocoagulation in treatment of diabetic retinopathy and diabetic macular edema with the frequent utilization of pharmacologic, including anti-vascular endothelial growth factor (VEGF), therapy.

Recent findings: Laser photocoagulation remains the gold-standard therapy for the effective, definitive treatment of PDR, and also is highly effective in the management of DME. However, numerous recent studies have demonstrated the clinical efficacy and improved functional and anatomic outcomes of combination therapy with pharmacologic treatment. Continuing innovations in laser technology and improved understanding of laser-retinal interactions and pathophysiology demonstrate that laser therapy will continue to play a critical role in the treatment of diabetic retinopathy and diabetic macular edema for many years to come.

Keywords: Diabetic macular edema; Diabetic retinopathy; Focal laser photocoagulation; Panretinal photocoagulation; Retinal laser therapy; Selective retinal therapy.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use
  • Diabetes Mellitus*
  • Diabetic Retinopathy* / drug therapy
  • Humans
  • Laser Coagulation
  • Laser Therapy*
  • Macular Edema* / drug therapy

Substances

  • Angiogenesis Inhibitors