Comparison of atlas-based auto-segmentation accuracy for radiotherapy in prostate cancer

Takahiro Aoyama; Hidetoshi Shimizu; Tomoki Kitagawa; Kazushi Yokoi; Yutaro Koide; Hiroyuki Tachibana; Kojiro Suzuki; Takeshi Kodaira

doi:10.1016/j.phro.2021.08.002

Comparison of atlas-based auto-segmentation accuracy for radiotherapy in prostate cancer

Phys Imaging Radiat Oncol. 2021 Aug 25:19:126-130. doi: 10.1016/j.phro.2021.08.002. eCollection 2021 Jul.

Authors

Takahiro Aoyama^{1

2}, Hidetoshi Shimizu¹, Tomoki Kitagawa¹, Kazushi Yokoi¹, Yutaro Koide¹, Hiroyuki Tachibana¹, Kojiro Suzuki³, Takeshi Kodaira¹

Affiliations

¹ Department of Radiation Oncology, Aichi Cancer Centre, 1-1 Kanokoden, Chikusa-Ku, Nagoya, Aichi 464-8681, Japan.
² Graduate School of Medicine, Aichi Medical University, 1-1 Yazako-karimata, Nagakute, Aichi 480-1195, Japan.
³ Department of Radiology, Aichi Medical University, 1-1 Yazako-karimata, Nagakute, Aichi 480-1195, Japan.

Abstract

Atlas-based auto-segmentation (ABS) procedure used in radiotherapy can be classified into two groups, one using one atlas per patient (sSM) and the other using multiple atlases (sMM). This study evaluated auto-contouring accuracy and contouring time in patients with prostate cancer using the two procedures. The Dice similarity coefficient of sMM was significantly better than that of sSM (prostate [median, 0.81 (range, 0.66-0.91) vs. 0.64 (0.27-0.71), p < 0.01], seminal vesicles [0.49 (0.31-0.80) vs. 0.18 (0.01-0.60), p < 0.05], and rectum [0.81 (0.37-0.91) vs. 0.57 (0.31-0.77), p < 0.01]). The median contouring times were 2.6 (sMM) and 1.3 min (sSM).

Keywords: ABS, atlas-based auto-segmentation; Atlas-based auto-segmentation; CT, computed tomography; Contouring; DSC, Dice similarity coefficient; IMRT, intensity-modulated radiation therapy; Interobserver variation; Prostate cancer; Radiation oncology; TPS, treatment planning system.