A rare case of invasive pulmonary aspergillosis presenting as organizing pneumonia due to Aspergillus niger in an immunocompetent host

Raphaël Schils; Antoine Altdorfer; Filip Moerman; Thierry Weber; Michèle De Waele; Johan Maertens; Benoit F Pirotte

doi:10.1016/j.rmcr.2021.101503

A rare case of invasive pulmonary aspergillosis presenting as organizing pneumonia due to Aspergillus niger in an immunocompetent host

Respir Med Case Rep. 2021 Aug 25:34:101503. doi: 10.1016/j.rmcr.2021.101503. eCollection 2021.

Authors

Raphaël Schils¹, Antoine Altdorfer², Filip Moerman², Thierry Weber³, Michèle De Waele⁴, Johan Maertens⁵, Benoit F Pirotte²

Affiliations

¹ Department of Internal Medicine and Infectious Diseases, Liège University Hospital, 4000, Liège, Belgium.
² Department of Internal Medicine and Infectious Diseases, CHR de la Citadelle, 4000, Liège, Belgium.
³ Department of Pneumology, CHR de la Citadelle, 4000, Liège, Belgium.
⁴ Department of Cardiothoracic Surgery, CHR de la Citadelle, 4000, Liège, Belgium.
⁵ Department of Hematology, University Hospital Leuven, 3000, Leuven, Belgium.

Abstract

Invasive pulmonary aspergillosis associated with organizing pneumonia is increasingly described and mainly affects the immunocompromised individual. Most of Aspergillus invasive infections in both immunocompetent and immunocompromised patients are attributed to Aspergillus fumigatus. Herein we describe a clinical case of pulmonary Aspergillus niger infection presenting as an organizing pneumonia in an immunocompetent patient. A wedge resection and two successive cures of azoles (voriconazole 6 weeks then itraconazole 6 weeks) were necessary for the patient to be totally recovered. The association of OP and IPA is rare. The involvement of A. niger makes it even rarer, this is the reason why we decided to report on this case.

Keywords: Aspergillus niger; Invasive pulmonary aspergillosis; Organizing pneumonia.

Publication types

Case Reports