Study of factors related to recurrence within 30 days after pneumonia treatment for community-onset pneumonia

Abstract

Introduction: It is not uncommon for patients hospitalized with pneumonia to experience an early relapse. Here, we investigated the factors related to pneumonia recurrence in Japan.

Purpose: We aimed to elucidate the factors related to early recurrence after completion of pneumonia treatment.

Methods: We examined 696 patients with community-acquired pneumonia (CAP) and nursing and healthcare-associated pneumonia (NHCAP) who were admitted to our hospital between October 2010 and February 2018, excluding those who died during hospitalization. Logistic regression analysis was used to assess the endpoint of recurrence within 30 days after the end of antibiotic treatment.

Results: NHCAP, chronic lung disease and duration of antibiotic treatment were significant risk factors for recurrence of pneumonia within 30 days after antibiotic discontinuation. Aspiration pneumonia was not be a significant factor in the early recurrence of pneumonia.

Conclusions: Long-term use of antimicrobials may be a risk factor in early recurrence of pneumonia.

Keywords: Community-acquired pneumonia; Early recurrence of pneumonia; Nursing and healthcare-associated pneumonia.