A review on permanent implants for prostate brachytherapy with comparison between stranded and loose seeds

Jpn J Radiol. 2022 Feb;40(2):135-146. doi: 10.1007/s11604-021-01189-3. Epub 2021 Sep 4.

Abstract

A systematic literature review to validate the conclusions with regard to stranded seeds versus loose seeds. Published data for this review were identified by searching the PubMed databases. PD90, PV100, PV150, UD30, and RV100 acquired during the perioperative period and the postoperative period were analyzed by meta-analysis. Based on these studies, in addition to the reduction of migration and displacement, stranded seeds had some dosimetric advantages, especially in dose homogeneity and coverage of target area due to its connection characteristics. We also noticed implanted seeds usually excessive both in stranded seeds group and loose seed group. Intraoperatively built custom links will prolong operation time, with the proficiency of technology, the prolonged time gradually decreases.

Keywords: Dosimetry; IBCL; Loose seeds; Meta-analysis; Migration; Stranded seeds; bNED.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Brachytherapy*
  • Humans
  • Male
  • Prostate
  • Prostatic Neoplasms* / diagnostic imaging
  • Prostatic Neoplasms* / radiotherapy
  • Prostatic Neoplasms* / surgery
  • Radiometry
  • Radiotherapy Dosage