Cardiovascular system and coronavirus disease-2019 (COVID-19): mutual injuries and unexpected outcomes

Eman Sobh; Muhammad Saad Reihan; Tamer M S Hifnawy; Khloud Gamal Abdelsalam; Sohaila Sabry Awad; Nehal Mostafa Hamed Mahmoud; Nariman A Sindi; Hani A Alhadrami

doi:10.1186/s43044-021-00202-4

Cardiovascular system and coronavirus disease-2019 (COVID-19): mutual injuries and unexpected outcomes

Egypt Heart J. 2021 Sep 3;73(1):77. doi: 10.1186/s43044-021-00202-4.

Authors

Eman Sobh^{1

2}, Muhammad Saad Reihan^{3

4}, Tamer M S Hifnawy⁵, Khloud Gamal Abdelsalam⁶, Sohaila Sabry Awad⁷, Nehal Mostafa Hamed Mahmoud⁸, Nariman A Sindi⁹, Hani A Alhadrami^{9

10}

Affiliations

¹ Chest Diseases Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt. emansobh2012@gmail.com.
² Respiratory Therapy Department, College of Medical Rehabilitation Sciences, Taibah University, Medina, Saudi Arabia. emansobh2012@gmail.com.
³ Cardiology Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.
⁴ Alghad International College of Applied Medical Sciences, Jeddah, Saudi Arabia.
⁵ Public Health and Community Medicine Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
⁶ Biochemistry Unit, Chemistry Department, Faculty of Science, Damanhour University, Damanhour, Egypt.
⁷ Independent Researcher, Bachelor Degree of Biochemistry, Faculty of Science, Cairo University, Cairo, Egypt.
⁸ Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
⁹ Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
¹⁰ Special Infectious Agent Unit, King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.

Abstract

Background: Cardiovascular system involvement in coronavirus disease-2019 (COVID-19) has gained great interest in the scientific community.

Main body: Several studies reported increased morbidity and mortality among COVID-19 patients who had comorbidities, especially cardiovascular diseases like hypertension and acute coronary syndrome (ACS). COVID-19 may be associated with cardiovascular complications as arrhythmia, myocarditis, and thromboembolic events. We aimed to illustrate the interactions of COVID-19 disease and the cardiovascular system and the consequences on clinical decision as well as public health.

Conclusions: COVID-19 has negative consequences on the cardiovascular system. A high index of suspicion should be present to avoid poor prognosis of those presenting with unusual presentation.

Keywords: Cardiovascular dysfunction; Cardiovascular function; Coronavirus disease; Public health implications; SARS-CoV-2.

Publication types

Review