Aspergillus lentulus is a drug-resistant species that is phenotypically similar to A. fumigatus. It was discovered as a cause of azole-breakthrough disease, consistent with in vitro resistance. Clinical labs can misidentify the species as fumigatus based on phenotypic typing. We describe 4 recent cases and provide a brief review.
Keywords: Aspergillus lentulus; DNA sequencing; MALDI-TOF MS; cryptic species; multidrug resistance; pulmonary aspergillosis.
© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.