Pre-hospital transfusion of post-traumatic hemorrhage: Medical and regulatory aspects

Transfus Clin Biol. 2021 Nov;28(4):391-396. doi: 10.1016/j.tracli.2021.08.345. Epub 2021 Aug 28.

Abstract

Data of good methodological quality have recently become available to support prehospital use of transfusion in the severe trauma setting. Consistent with recent guidelines for the implementation of damage control resuscitation in the hospital in this setting and in the wake of numerous cohort study data from wartime medicine, they are now guided by recent guidelines for the use of freeze-dried plasma. The main difficulties to overcome in order to implement a practice are of a regulatory and logistic nature.

Keywords: Blessure; Blood; Emergency; Injury; Medical services; Plasma; Prehospital; Prehospital care; Préhospitalier; Sang; Services médicaux; Soins préhospitaliers; Transfusion; Trauma; Traumatisme; Urgence.

MeSH terms

  • Cohort Studies
  • Emergency Medical Services*
  • Hemorrhage / etiology
  • Hemorrhage / therapy
  • Hospitals
  • Humans
  • Resuscitation
  • Wounds and Injuries* / complications
  • Wounds and Injuries* / therapy