Conjunctival myxoma: A systematic review of a rare tumor

Surv Ophthalmol. 2022 May-Jun;67(3):729-740. doi: 10.1016/j.survophthal.2021.08.007. Epub 2021 Aug 27.

Abstract

Conjunctival myxoma is an uncommon benign tumor that may develop as a localized disease or as part of the Carney complex, in which case it can cause significant morbidity and mortality. Conjunctival myxomas can mimic other pure or mixed tumors and are often overlooked in clinical practice. Histopathological studies are essential for diagnosis; however, controversy regarding their pathological and immunohistochemical features makes the diagnostic process more difficult. Because of the importance of correctly classifying these conjunctival tumors, as well as recognizing when a systematic screening is required owing to the possible association with life-threatening diseases, we comprehensively evaluate the literature on this rare entity based on a systematic approach.

Keywords: Conjunctival myxoid tumor, conjunctival tumor; Conjunctival myxoma; Ocular surface tumors; Systematic review.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Conjunctival Neoplasms* / diagnosis
  • Conjunctival Neoplasms* / pathology
  • Humans
  • Myxoma* / diagnosis
  • Myxoma* / pathology