Liver Cirrhosis, Etiology and Clinical Characteristics Disparities Among Minority Population

J Immigr Minor Health. 2022 Oct;24(5):1122-1128. doi: 10.1007/s10903-021-01263-y. Epub 2021 Aug 28.

Abstract

Liver cirrhosis (LC) is a common disease with varied primary causes and ethnic disparities. Clinical characteristics and outcomes of Arab Bedouin (AB) and Jewish patients with LC were retrospective collected and compared. We included 1048 patients, 95 (9%) Arab Bedouin and 953 (91%) Jewish patients. The incidence of cirrhosis was much lower among AB. Age at diagnosis was 47 ± 18 years among Bedouins compared to 61 ± 13 years (p < 0.001) among Jews. The most frequent causes of cirrhosis among Bedouin patients were fatty liver 21.1%, cryptogenic 20%, hepatitis B 17.9% and autoimmune hepatitis 15.8%, while hepatitis C (39.2%), fatty liver (17.2%) and alcoholic liver disease (14.4%) were most common among Jewish patients. An all-cause mortality of 48.4% was observed in AB patients compared to 66.4% in Jewish patients (p < 0.001). Significant disparities regarding incidence, clinical characteristics and outcomes of cirrhosis among Arab Bedouin compared with Jewish population were found.

Keywords: Arab Bedouin; Cirrhosis; Complications; Jews; Mortality.

MeSH terms

  • Arabs
  • Fatty Liver*
  • Humans
  • Israel / epidemiology
  • Jews*
  • Liver Cirrhosis
  • Retrospective Studies