New Insights into the Biology of the Emerging Tembusu Virus

Rodolphe Hamel; Thipruethai Phanitchat; Sineewanlaya Wichit; Ronald Enrique Morales Vargas; Jiraporn Jaroenpool; Cheikh Tidiane Diagne; Julien Pompon; Dorothée Missé

doi:10.3390/pathogens10081010

New Insights into the Biology of the Emerging Tembusu Virus

Pathogens. 2021 Aug 10;10(8):1010. doi: 10.3390/pathogens10081010.

Authors

Rodolphe Hamel¹, Thipruethai Phanitchat², Sineewanlaya Wichit³, Ronald Enrique Morales Vargas², Jiraporn Jaroenpool⁴, Cheikh Tidiane Diagne¹, Julien Pompon¹, Dorothée Missé¹

Affiliations

¹ MIVEGEC, Univ Montpellier, IRD, CNRS, 34000 Montpellier, France.
² Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
³ Department of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Nakhon Pathom 73170, Thailand.
⁴ Medical Technology Department, School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand.

Abstract

Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained, for a long time, in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its emergence on a large scale in Asia or even its spillover into the human population is becoming more and more significant. This review aims to report current knowledge on TMUV from viral particle organization to the development of specific vaccines and therapeutics, with a particular focus on host-virus interactions.

Keywords: TMUV; emergent arboviruses; host-pathogen interactions; vector; zoonosis.

Publication types

Review

Abstract

Publication types

Grants and funding