Understanding and Exploiting Post-Translational Modifications for Plant Disease Resistance

Biomolecules. 2021 Jul 30;11(8):1122. doi: 10.3390/biom11081122.

Abstract

Plants are constantly threatened by pathogens, so have evolved complex defence signalling networks to overcome pathogen attacks. Post-translational modifications (PTMs) are fundamental to plant immunity, allowing rapid and dynamic responses at the appropriate time. PTM regulation is essential; pathogen effectors often disrupt PTMs in an attempt to evade immune responses. Here, we cover the mechanisms of disease resistance to pathogens, and how growth is balanced with defence, with a focus on the essential roles of PTMs. Alteration of defence-related PTMs has the potential to fine-tune molecular interactions to produce disease-resistant crops, without trade-offs in growth and fitness.

Keywords: SUMOylation; defence; phosphorylation; plant immunity; post-translational modifications; ubiquitination.

Publication types

  • Review

MeSH terms

  • Disease Resistance / genetics
  • Host-Pathogen Interactions / genetics
  • Host-Pathogen Interactions / immunology*
  • Phosphorylation
  • Plant Diseases / immunology*
  • Plant Diseases / microbiology
  • Plant Diseases / virology
  • Plant Immunity / genetics
  • Plant Proteins / classification
  • Plant Proteins / genetics
  • Plant Proteins / immunology*
  • Plants / immunology*
  • Plants / metabolism
  • Plants / microbiology
  • Plants / virology
  • Protein Processing, Post-Translational*
  • Signal Transduction
  • Sumoylation
  • Ubiquitination

Substances

  • Plant Proteins