Torque teno mini virus as a cause of childhood acute promyelocytic leukemia lacking PML/RARA fusion

Blood. 2021 Nov 4;138(18):1773-1777. doi: 10.1182/blood.2021011677.

Affiliations

¹ Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
² Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
³ Interdepartmental Center Alma Mater Institute on Healthy Planet.
⁴ Department of Medical and Surgical Sciences.
⁵ Unit of Holobiont Microbiome and Microbiome Engineering, Department of Pharmacy and Biotechnology.
⁶ Residency School of Pediatrics, and.
⁷ Residency School of Hematology, University of Bologna, Bologna, Italy.

PMID: 34432867
DOI: 10.1182/blood.2021011677

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Anelloviridae / pathogenicity
Anelloviridae / physiology
Antineoplastic Agents / therapeutic use
Child
Female
Humans
Karyotype
Leukemia, Promyelocytic, Acute / genetics*
Leukemia, Promyelocytic, Acute / pathology
Leukemia, Promyelocytic, Acute / therapy
Oncogene Proteins, Fusion / genetics*
Oncogenic Viruses / pathogenicity
Oncogenic Viruses / physiology*
Retinoic Acid Receptor alpha*
Torque teno virus / pathogenicity
Torque teno virus / physiology*
Tretinoin / therapeutic use

Substances

Antineoplastic Agents
Oncogene Proteins, Fusion
Retinoic Acid Receptor alpha
promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein
Tretinoin