Microbial populations typically show a large degree of intra-population diversity. This diversity is intertwined with the structure of the population. Here, we discuss endogenous and exogenous drivers of population structure in microbes and how the population structure can affect evolutionary dynamics and vice versa. Endogenous structure, which can be genetic or demographic, is driven by the ecology and evolutionary dynamics within the population. Exogenous structure is typically driven by the spatial and temporal properties of the environment. A particular interesting case arises when also this exogenous structure experiences feedbacks from the microbial population.
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