Stem cell niche signaling goes both ways

Amelie A Raz; Yukiko M Yamashita

doi:10.1016/j.devcel.2021.08.003

Stem cell niche signaling goes both ways

Dev Cell. 2021 Aug 23;56(16):2267-2268. doi: 10.1016/j.devcel.2021.08.003.

Authors

Amelie A Raz¹, Yukiko M Yamashita²

Affiliations

¹ Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Howard Hughes Medical Institute, Cambridge, MA, USA. Electronic address: araz@wi.mit.edu.
² Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Howard Hughes Medical Institute, Cambridge, MA, USA; Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: yukikomy@wi.mit.edu.

Abstract

Stem cell niches are well-characterized factories of signaling information, but niche cells themselves also rely on their neighbors for fate maintenance. In this issue of Developmental Cell, Herrera et al. reveal bi-directional communication between Drosophila testis niche "hub" cells and somatic cyst stem cells.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Drosophila
Drosophila Proteins* / genetics
Germ Cells
Male
Stem Cell Niche*
Stem Cells
Testis

Substances

Drosophila Proteins

Abstract

Publication types

MeSH terms

Substances

Grants and funding