Meet the authors: Michael Ranes and Sebastian Guettler

Mol Cell. 2021 Aug 19;81(16):3237-3240. doi: 10.1016/j.molcel.2021.08.002.

Abstract

We talk to first and last authors Michael Ranes and Sebastian Guettler about their paper, "Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation," how questions at conferences drove the work, the research in the Guettler lab, and Michael's experience as a Black scientist and his hopes for the future.

Publication types

  • Autobiography
  • Historical Article
  • Interview

MeSH terms

  • Axin Protein / chemistry
  • Axin Protein / genetics*
  • History, 21st Century
  • Humans
  • Male
  • Molecular Biology / history*
  • Phosphorylation / genetics
  • Protein Processing, Post-Translational / genetics*
  • Ubiquitination / genetics

Substances

  • Axin Protein

Personal name as subject

  • Michael Ranes
  • Sebastian Guettler