Two-dimensional (2D) hybrid perovskites, as newly emerging materials, have become the center of attention in optoelectronic fields within a few years because of their unique optoelectronic properties, including tunable bandgap, long carrier diffusion length, and high absorption coefficient. 2D perovskite-based van der Waals heterostructures via integration of 2D perovskites with other layered materials provide new platforms for many optoelectronic devices with prominent performance, such as photodetectors, light-emitting diodes (LEDs), and phototransistors. In this Perspective, the unique properties of 2D perovskites will be first introduced to explore why this material is attractive and popular. Subsequently, various types of heterostructures based on 2D perovskites will be illustrated, including the heterostructure construction approaches as well as their optical and optoelectronic applications. Finally, potential research directions based on 2D perovskite heterostructures are also proposed.