Insights from the degradation mechanism of cyclin D into targeted therapy of the cancer cell cycle

Signal Transduct Target Ther. 2021 Aug 19;6(1):311. doi: 10.1038/s41392-021-00732-y.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Proliferation / drug effects*
  • Cyclin D / antagonists & inhibitors
  • Cyclin D / genetics*
  • Cyclin-Dependent Kinase 4 / genetics
  • Cyclin-Dependent Kinase 6 / genetics
  • Humans
  • Molecular Targeted Therapy*
  • Multiprotein Complexes / antagonists & inhibitors
  • Neoplasms / drug therapy*
  • Neoplasms / genetics
  • Neoplasms / pathology

Substances

  • Cyclin D
  • Multiprotein Complexes
  • CDK4 protein, human
  • CDK6 protein, human
  • Cyclin-Dependent Kinase 4
  • Cyclin-Dependent Kinase 6