Delayed Expulsion of biliary cast after hepaticojejunostomy for post-liver transplantation biliary stricture-better cut than canulate?

Pediatr Transplant. 2021 Dec;25(8):e14115. doi: 10.1111/petr.14115. Epub 2021 Aug 19.

Abstract

Background: Biliary strictures after living donor liver transplantation (LDLT) are a significant cause of post-transplant morbidity. Endoscopic therapy is usually the first choice of treatment though surgical treatment may provide better biliary drainage.

Methods: We report a case of LDLT performed in a child for acute liver failure who developed an anastomotic biliary stricture with biliary cast formation. We performed a Roux en Y hepaticojejunostomy to treat the stricture.

Results: Allograft function improved after surgery with no further episodes of cholangitis. Two months after the surgery, the child passed a large biliary cast in the stools. This reiterates the advantage of wide biliary drainage provided through surgical therapy.

Conclusions: Surgery for biliary strictures following LDLT may provide superior long term biliary drainage- especially when biliary casts are present.

Keywords: BCS; LDLT; hepaticojejunostomy.

Publication types

  • Case Reports

MeSH terms

  • Anastomosis, Roux-en-Y*
  • Cholestasis / surgery*
  • Constriction, Pathologic
  • Drainage
  • Female
  • Humans
  • Infant
  • Liver Failure / surgery
  • Liver Transplantation / methods*
  • Living Donors
  • Postoperative Complications / surgery*