COVID-related psychological distress fully mediates the association from social impact to sleep disturbance among patients with chronic schizophrenia

Sci Rep. 2021 Aug 16;11(1):16524. doi: 10.1038/s41598-021-96022-2.

Abstract

The aims of the current study were to identify factors associated with sleep disturbance and Coronavirus disease-19 related psychological distress (CPD), and to develop a conceptual model to verify the mediating effect of CPD on the association between social impact and sleep disturbance. This study recruited patients with schizophrenia. Factors associated with the level of sleep disturbance and CPD were identified using univariate linear regression, and further selected into a stepwise multivariate linear regression model. Using structural equation modeling, a mediation model was developed to test the mediating effect of CPD on the association between social impact and sleep disturbance. After estimating with the stepwise and bootstrap regression, higher levels of CPD were associated with higher levels of social anxiety and subjects without a regular diet. Sleep disturbance was associated with a higher level of social anxiety, a history of psychological trauma, chronic disease, and those who did not smoke. The final model confirmed the mediating effects of CPD; whereas, the direct effect from social impact to sleep disturbance did not reach statistical significance. The current study manifests the crucial role of CPD on the association between social impact and sleep disturbance, and timely intervention for CPD is warranted.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • COVID-19 / epidemiology
  • COVID-19 / psychology*
  • COVID-19 / transmission
  • Cross-Sectional Studies
  • Female
  • Health Services Accessibility
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Psychological Distress*
  • Risk Factors
  • Schizophrenia / complications*
  • Schizophrenic Psychology
  • Self Report / statistics & numerical data
  • Sleep Wake Disorders / diagnosis
  • Sleep Wake Disorders / epidemiology
  • Sleep Wake Disorders / psychology*
  • Social Change*
  • Taiwan / epidemiology