Late-Onset Giant Cell Myocarditis Due to Enterovirus During Treatment With Immune Checkpoint Inhibitors

Mariana Mirabel; Domitille Callon; Patrick Bruneval; Anne-Laure Lebreil; Elie Mousseaux; Stéphane Oudard; Jean-Sébastien Hulot; Laurent Andreoletti

doi:10.1016/j.jaccao.2020.05.022

Late-Onset Giant Cell Myocarditis Due to Enterovirus During Treatment With Immune Checkpoint Inhibitors

JACC CardioOncol. 2020 Sep 15;2(3):511-514. doi: 10.1016/j.jaccao.2020.05.022. eCollection 2020 Sep.

Authors

Mariana Mirabel^{1

2}, Domitille Callon^{3

4}, Patrick Bruneval^{1

5}, Anne-Laure Lebreil³, Elie Mousseaux^{1

6}, Stéphane Oudard^{1

7}, Jean-Sébastien Hulot^{1

2

8}, Laurent Andreoletti^{3

9}

Affiliations

¹ Université de Paris, Paris Cardiovascular Research Center PARCC, INSERM, Paris, France.
² Cardio-oncology unit, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
³ Université de Reims Champagne Ardenne, Cardiovir EA-4684, Reims, France.
⁴ CHU Reims, Hôpital Robert Debré, Pathology Department, Reims, France.
⁵ Assistance Publique-Hôpitaux de Paris, APHP Centre, Hôpital Européen Georges Pompidou, Pathology, Paris, France.
⁶ Cardio-vascular imaging, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
⁷ Medical Oncology, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
⁸ Centre d'Investigations Cliniques CIC1418, AP-HP, Hôpital Européen Georges Pompidou, Paris, France.
⁹ CHU Reims, Hôpital Robert Debré, Virology Department, Reims, France.

No abstract available

Keywords: CTLA-4, cytotoxic T lymphocyte-associated antigen-4; EMB, endomyocardial biopsy; EV, enterovirus; ICI, immune checkpoint inhibitors; LVEF, left ventricular ejection fraction; PD-1, programmed cell death-1; PD-L1, programmed cell death-ligand 1; enterovirus; giant cell myocarditis; imaging; immune checkpoint inhibitors; immunotherapy; myocarditis.

Publication types

Review