Depression symptoms as longitudinal predictors of the psychological impact of COVID-19 pandemic in hypertensive patients

Sci Rep. 2021 Aug 13;11(1):16496. doi: 10.1038/s41598-021-96165-2.

Abstract

COVID-19 has brought considerable changes and caused critical psychological responses, especially among frail populations. So far, researchers have explored the predictive effect of diverse factors on pandemic-related psychological distress, but none have focused on the impact of prior depression and anxiety symptomatology adopting an extended (10-year) longitudinal design. 105 patients aged over 60, affected by hypertension who participated in a previous longitudinal study were assessed through a follow-up telephone structured interview. The Hospital Anxiety and Depression Scale (HADS) and the Impact of Event Scale-Revised (IES-R) were used for assessing depression and anxiety symptoms and the psychological impact of COVID-19, respectively. Multiple linear regression analyses were conducted. At the assessment, participants did not report clinically relevant depression, anxiety, and psychological pandemic-related distress symptoms. However, significant mean differences between baseline and current follow-up evaluations for both depression and anxiety were found, reflecting a decrease in symptomatology over time (p < .001). Baseline depression symptoms (β = 1.483, p = .005) significantly predicted the psychological impact of COVID-19 after 10 years. Conversely, their decrease (β = -1.640, p < .001) and living with others (β = -7.274, p = .041) significantly contributed to lower psychological distress scores. Our findings provide insight into the predisposing influence of depressive symptoms on pandemic-related psychological distress ten years later. Preventive interventions and strategies considering these factors are needed to better pre-empt the severe mental consequences of the pandemic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anxiety Disorders / epidemiology*
  • COVID-19 / epidemiology
  • COVID-19 / psychology*
  • Depression / epidemiology*
  • Female
  • Humans
  • Hypertension
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Pandemics*
  • Stress Disorders, Post-Traumatic / epidemiology*
  • Surveys and Questionnaires