Visual Plasticity in Adulthood: Perspectives from Hebbian and Homeostatic Plasticity

Neuroscientist. 2023 Feb;29(1):117-138. doi: 10.1177/10738584211037619. Epub 2021 Aug 12.

Abstract

The visual system retains profound plastic potential in adulthood. In the current review, we summarize the evidence of preserved plasticity in the adult visual system during visual perceptual learning as well as both monocular and binocular visual deprivation. In each condition, we discuss how such evidence reflects two major cellular mechanisms of plasticity: Hebbian and homeostatic processes. We focus on how these two mechanisms work together to shape plasticity in the visual system. In addition, we discuss how these two mechanisms could be further revealed in future studies investigating cross-modal plasticity in the visual system.

Keywords: Hebbian plasticity; blindness; homeostasis; plasticity; reactivation; visual deprivation; visual perceptual learning.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Homeostasis
  • Humans
  • Neuronal Plasticity*
  • Visual Cortex*