Blood and Marrow Transplant Clinical Trials Network Study 1102 heralds a new era in hematopoietic cell transplantation in high-risk myelodysplastic syndromes: Challenges and opportunities in implementation

Cancer. 2021 Dec 1;127(23):4339-4347. doi: 10.1002/cncr.33826. Epub 2021 Aug 10.

Abstract

People who have advanced myelodysplastic syndromes (MDS) may live longer if they get a bone marrow transplant (BMT) instead of other therapies. However, only 15% of people with MDS actually get BMT. Experts say community physicians and transplant physicians should team up with insurance companies and patient advocacy groups to 1) spread this news about lifesaving advances in BMT, 2) ensure that everyone can afford health care, 3) provide emotional support for patients and families, 4) help patients and families get transportation and housing if they need to travel for transplant, and 5) improve care for people of under-represented racial and ethnic backgrounds.

Keywords: MDS; allogeneic hematopoietic cell transplantation; expanded access; myelodysplastic syndromes; reduce intensity conditioning.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Bone Marrow
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Myelodysplastic Syndromes* / therapy
  • Transplantation Conditioning
  • Transplantation, Homologous