An Appraisal of the Current Scenario in Vaccine Research for COVID-19

Viruses. 2021 Jul 18;13(7):1397. doi: 10.3390/v13071397.

Abstract

The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectious agent, SARS-CoV-2, still remains obscure, ongoing genomic studies have been successful in identifying its genomic sequence and the presenting antigen. These may serve as promising, potential therapeutic targets in the effective management of COVID-19. In an attempt to establish herd immunity, massive efforts have been directed and driven toward developing vaccines against the SARS-CoV-2 pathogen. This review, in this direction, is aimed at providing the current scenario and future perspectives in the development of vaccines against SARS-CoV-2.

Keywords: COVID-19; SARS-CoV-2; immunity; therapeutic targets; vaccines.

Publication types

  • Review

MeSH terms

  • COVID-19 / epidemiology
  • COVID-19 / immunology*
  • COVID-19 / prevention & control*
  • COVID-19 / virology
  • COVID-19 Vaccines / immunology*
  • Humans
  • Immunity
  • Immunity, Herd
  • SARS-CoV-2 / isolation & purification
  • Vaccination

Substances

  • COVID-19 Vaccines