Apligraf as an Alternative to Skin Grafting in the Pediatric Population

Cureus. 2021 Jul 7;13(7):e16226. doi: 10.7759/cureus.16226. eCollection 2021 Jul.

Abstract

Split-thickness skin grafting and healing by secondary intention are the most common options for the treatment of full-thickness skin injuries. This case explores Apligraf (Organogenesis Inc., Canton, Massachusetts) as an alternative treatment for full-thickness skin injuries in the pediatric population. Apligraf, a bioengineered living cell construct, is an advanced wound care modality that is commonly used to treat chronic, nonhealing venous leg ulcers and diabetic foot ulcers. This case demonstrates Apligraf as a viable, if not superior, treatment option for full-thickness skin injury.

Keywords: apligraf; bioengineered living cell constructs; full thickness skin graft; full thickness wounds; pediatric plastic surgery; skin graft; split thickness skin graft.

Publication types

  • Case Reports