Current and Next Steps Toward Prediction of Human Dose for Gene Therapy Using Translational Dose-Response Studies

Affiliations

• ¹ Early Development Analytics, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA.
• ² Clinical Pharmacology and Pharmacometrics, CSL Behring, King of Prussia, Pennsylvania, USA.
• ³ Cell Therapy Pharmacology and Modeling, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, USA.
• ⁴ Translational Sciences, GentiBio, Cambridge, Massachusetts, USA.
• ⁵ Quantitative Clinical Pharmacology, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, USA.